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PPP5C Validated sgRNA vector

For research use only. Not intended for any clinical use.

Cat. No. :   SKO0700

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Cat. No. SKO0700
Description Creative Biogene develops and optimizes genome editing technology to produce stable genome edited mammalian cell lines serving a wide-range of R&D activities in areas of basic research, diagnostic and therapeutic development. Our premade SuperKO sgRNA vectors are tailor-made to target many different genes respectively. We have successfully constructed a series of knockout cell lines using those sgRNAs.
Gene Abbr PPP5C
Reporter mCherry
Promoter U6
Resistance Amp
Selection Ampicillin
Vector Type Lentiviral Expression
Vector Length 7677 bp
Target Gene PPP5C
Background This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
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