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NEFM Validated sgRNA vector

For research use only. Not intended for any clinical use.

Cat. No. :   SKO0629

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Cat. No. SKO0629
Description Creative Biogene develops and optimizes genome editing technology to produce stable genome edited mammalian cell lines serving a wide-range of R&D activities in areas of basic research, diagnostic and therapeutic development. Our premade SuperKO sgRNA vectors are tailor-made to target many different genes respectively. We have successfully constructed a series of knockout cell lines using those sgRNAs.
Gene Abbr NEFM
Reporter mCherry
Promoter U6
Resistance Amp
Selection Ampicillin
Vector Type Lentiviral Expression
Vector Length 7677 bp
Target Gene NEFM
Background Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
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