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Mouse Whsc1 cDNA Clone(NM_175231.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL015133

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Gene Information

Cat. No. CDFL015133
Product Type cDNA clone
Gene Abbr Whsc1
Species Mouse
Size 10 ug
Vector pCMV6Entry
Target Gene WHSC1
Background This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq, Jul 2008]
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