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Mouse Wdr35 cDNA Clone(NM_001159527.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG019877

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Gene Information

Cat. No. CDFG019877
Product Type cDNA clone
Gene Abbr Wdr35
Species Mouse
ORF Size 3513bp
Size 10 ug
Vector pCMV6Entry
Target Gene WDR35
Background This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Two patients with Sensenbrenner syndrome / cranioectodermal dysplasia (CED) were identified with mutations in this gene, consistent with a possible ciliary function.[provided by RefSeq, Sep 2010]
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