Mouse Tsc22d1 ORF clone (NM_207652.2)

Name: Mouse Tsc22d1 ORF clone (NM_207652.2)
SKU: CDCH095778
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH095778

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Product Information

Gene Information

Cat. No.	CDCH095778
Description	Mus musculus TSC22 domain family, member 1 (Tsc22d1), transcript variant 1, mRNA.
Product Type	ORF clone
Gene Abbr	Tsc22d1
Species	Mouse
ORF Size	3234bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

TSC22D1

Background

This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]

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