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Mouse Tmx3 cDNA Clone(NM_198295.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL014075

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Gene Information

Cat. No. CDFL014075
Product Type cDNA clone
Gene Abbr Tmx3
Species Mouse
Size 10 ug
Vector pCMV6Entry
Target Gene TMX3
Background This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The canonical protein encoded by this gene has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This gene is expressed in many tissues but has its highest expression in heart and skeletal muscle. It is expressed in the retinal neuroepithelium and lens epithelium in the developing murine eye and haploinsufficiency of this gene in humans and zebrafish is associated with microphthalmia. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017]
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