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Mouse Tmc8 cDNA Clone(NM_001195088.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG021663

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Product Information

Gene Information

Cat. No. CDFG021663
Product Type cDNA clone
Gene Abbr Tmc8
Species Mouse
ORF Size 2265bp
Size 10 ug
Vector pCMV6Entry
Target Gene TMC8
Background Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. [provided by RefSeq, Jul 2008]
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