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Mouse Tfe3 ORF Clone(NM_172472.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR271051

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Gene Information

Cat. No. CDCR271051
Product Type ORF Clone
Gene Abbr Tfe3
Species Mouse
Tag C-terminal Myc-DDK
ORF Size 1718 bp
Vector pCMV6-Entry
Target Gene TFE3
Background This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
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