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Mouse Ston1 cDNA Clone(NM_029858.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL013208

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Product Information

Gene Information

Cat. No. CDFL013208
Product Type cDNA clone
Gene Abbr Ston1
Species Mouse
Size 10 ug
Vector pCMV6Entry
Target Gene STON1
Background Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of an N-terminal proline-rich domain, a central region of homology specific to the human stoned B-like proteins, and a C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes. Read-through transcription of this gene into the neighboring downstream gene, which encodes TFIIA-alpha/beta-like factor, generates a transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
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