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Mouse Spata18 cDNA Clone(NM_178387.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL012916

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Product Information

Gene Information

Cat. No. CDFL012916
Product Type cDNA clone
Gene Abbr Spata18
Species Mouse
Size 10 ug
Vector pCMV6Entry
Target Gene SPATA18
Background This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
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