Mouse Sirt4 ORF clone (NM_001167691.1)

Name: Mouse Sirt4 ORF clone (NM_001167691.1)
SKU: CDCH080424
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH080424

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Product Information

Gene Information

Cat. No.	CDCH080424
Description	Mus musculus sirtuin 4 (silent mating type information regulation 2 homolog) 4 (S. cerevisiae) (Sirt4), transcript variant 1, mRNA.
Product Type	ORF clone
Gene Abbr	Sirt4
Species	Mouse
ORF Size	1002bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

SIRT4

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008]

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