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Mouse Siglec1 ORF clone (NM_011426.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCH080174

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Product Information

Gene Information

Cat. No. CDCH080174
Description Mus musculus sialic acid binding Ig-like lectin 1, sialoadhesin (Siglec1), mRNA.
Product Type ORF clone
Gene Abbr Siglec1
Species Mouse
ORF Size 5106bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Target Gene SIGLEC1
Background This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. The protein plays an important role in multiple human diseases and bacterial and viral infections has been shown to enhance SARS-CoV-2 infection. [provided by RefSeq, Dec 2021]
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