Pages
Products

Mouse Shc1 cDNA Clone(NM_001113331.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG019173

Inquire for Price

Product Information

Gene Information

Cat. No. CDFG019173
Product Type cDNA clone
Gene Abbr Shc1
Species Mouse
ORF Size 1740bp
Size 10 ug
Vector pCMV6Entry
Target Gene SHC1
Background This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Needs improvement

Satisfaction

General satisfaction

Very satisfaction