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Mouse Sec31a cDNA Clone(NM_026969.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL012049

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Gene Information

Cat. No. CDFL012049
Product Type cDNA clone
Gene Abbr Sec31a
Species Mouse
Size 10 ug
Vector pCMV6Entry
Target Gene SEC31A
Background The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
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