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Mouse Saa2 cDNA Clone(NM_011314.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL011879

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Gene Information

Cat. No. CDFL011879
Product Type cDNA clone
Gene Abbr Saa2
Species Mouse
Size 10 ug
Vector pCMV6Entry
Target Gene SAA2
Background This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Finally, antimicrobial activity against S. aureus and E. coli resides in the N-terminal portion of the mature protein. [provided by RefSeq, Jul 2020]
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