Mouse SUN2 ORF clone(NM_001205346.1)

Name: Mouse SUN2 ORF clone(NM_001205346.1)
SKU: CDCH402898
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH402898

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Product Information

Gene Information

Cat. No.	CDCH402898
Product Type	ORF clone
Gene Abbr	SUN2
Species	Mouse
Host Cell	Bacterial
Source	Bacterial
ORF Size	3803bp
Size	1ug
Format	Clear Liquid
Vector	pORF
Buffer	10mM Tris-HCI, 1mM EDTA, pH8.0
Warning	pORF-mSun2 ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage	1 year when stored at -20°C or lower in a non-frost free freezer.

Target Gene

SUN2

Background

SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]

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