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Mouse Rapgef4 ORF clone (NM_001204165.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCH071654

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Gene Information

Cat. No. CDCH071654
Description Mus musculus Rap guanine nucleotide exchange factor (GEF) 4 (Rapgef4), transcript variant 1, mRNA.
Product Type ORF clone
Gene Abbr Rapgef4
Species Mouse
ORF Size 3036bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Target Gene RAPGEF4
Background Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane; and regulation of postsynapse organization. Predicted to act upstream of or within with a positive effect on hormone secretion. Predicted to act upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway; regulation of exocytosis; and secretion by cell. Predicted to be located in membrane. Predicted to be active in several cellular components, including glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; and postsynaptic density. Implicated in autistic disorder. [provided by Alliance of Genome Resources, Feb 2025]
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