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Mouse Ptprr ORF clone (NM_001161838.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCH069984

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Gene Information

Cat. No. CDCH069984
Description Mus musculus protein tyrosine phosphatase, receptor type, R (Ptprr), transcript variant 3, mRNA.
Product Type ORF clone
Gene Abbr Ptprr
Species Mouse
ORF Size 1239bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Target Gene PTPRR
Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]
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