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Mouse Ptpro ORF Clone(NM_011216.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR249972

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Product Information

Gene Information

Cat. No. CDCR249972
Product Type ORF Clone
Gene Abbr Ptpro
Species Mouse
Tag C-terminal TurboGFP
ORF Size 3681 bp
Size 10 ug
Vector pCMV6-AC-GFP
Target Gene PTPRO
Background This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer. [provided by RefSeq, May 2011]
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