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Mouse Prrg1 ORF clone (NM_001164275.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL149623

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Gene Information

Cat. No. CDCL149623
Description Mus musculus proline rich Gla (G-carboxyglutamic acid) 1 (Prrg1), transcript variant 2, mRNA.
Product Type ORF clone
Gene Abbr Prrg1
Species Mouse
ORF Size 654bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Target Gene PRRG1
Background This gene encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. This gene is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]
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