Mouse Prkd3 ORF clone (NM_001171004.1)

Name: Mouse Prkd3 ORF clone (NM_001171004.1)
SKU: CDCH067884
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH067884

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Product Information

Gene Information

Cat. No.	CDCH067884
Description	Mus musculus protein kinase D3 (Prkd3), transcript variant 1, mRNA.
Product Type	ORF clone
Gene Abbr	Prkd3
Species	Mouse
ORF Size	2673bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

PRKD3

Background

This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization. This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation, growth regulation of breast and prostate cancer cells, and vesicle trafficking. [provided by RefSeq, Jan 2015]

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