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Mouse Prdm12 cDNA Clone(NM_001123362.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG019382

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Gene Information

Cat. No. CDFG019382
Product Type cDNA clone
Gene Abbr Prdm12
Species Mouse
ORF Size 1098bp
Size 10 ug
Vector pCMV6Entry
Target Gene PRDM12
Background This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia. [provided by RefSeq, Mar 2017]
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