Mouse Ppm1b ORF clone (NM_001159497.1)

Name: Mouse Ppm1b ORF clone (NM_001159497.1)
SKU: CDCH066650
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH066650

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Product Information

Gene Information

Cat. No.	CDCH066650
Description	Mus musculus protein phosphatase 1B, magnesium dependent, beta isoform (Ppm1b), transcript variant 3, mRNA.
Product Type	ORF clone
Gene Abbr	Ppm1b
Species	Mouse
ORF Size	1173bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

PPM1B

Background

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008]

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