Mouse Pex3 cDNA Clone(NM_001164195.1)

Name: Mouse Pex3 cDNA Clone(NM_001164195.1)
SKU: CDFG020582
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFG020582

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Product Information

Gene Information

Cat. No.	CDFG020582
Product Type	cDNA clone
Gene Abbr	Pex3
Species	Mouse
ORF Size	1080bp
Size	10 ug
Vector	pCMV6Entry

Target Gene

PEX3

Background

The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). [provided by RefSeq, Oct 2008]

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