Mouse PTHLH ORF clone(NM_008970.3)

Name: Mouse PTHLH ORF clone(NM_008970.3)
SKU: CDCH395836
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH395836

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Product Information

Gene Information

Cat. No.	CDCH395836
Product Type	ORF clone
Gene Abbr	PTHLH
Species	Mouse
Host Cell	Bacterial
Source	Bacterial
ORF Size	1512bp
Size	1ug
Format	Clear Liquid
Vector	pORF
Buffer	10mM Tris-HCI, 1mM EDTA, pH8.0
Warning	pORF-mPthlh ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage	1 year when stored at -20°C or lower in a non-frost free freezer.

Target Gene

PTHLH

Background

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2). Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone. [provided by RefSeq, Nov 2013]

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