Transfected Stable Cell Lines
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Cat. No. : CDCL145639
| Cat. No. | CDCL145639 |
| Description | Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 3 (PAK3), transcript variant 5, mRNA. |
| Product Type | ORF clone |
| Gene Abbr | PAK3 |
| Species | Human |
| ORF Size | 1698bp |
| Format | purified plasmid |
| Vector | pDONR |
| Warning | Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function. |
| Target Gene | PAK3 |
| Background | The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of a non-syndromic form of X-linked intellectual disability. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2017] |
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