Mouse P4HA1 ORF clone (NM_000917.3)

Name: Mouse P4HA1 ORF clone (NM_000917.3)
SKU: CDCL145377
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL145377

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Product Information

Gene Information

Cat. No.	CDCL145377
Description	Homo sapiens prolyl 4-hydroxylase, alpha polypeptide I (P4HA1), transcript variant 1, mRNA.
Product Type	ORF clone
Gene Abbr	P4HA1
Species	Human
ORF Size	1605bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

P4HA1

Background

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

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