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Mouse P2rx6 ORF clone (NM_001159561.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL145305

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Product Information

Gene Information

Cat. No. CDCL145305
Description Mus musculus purinergic receptor P2X, ligand-gated ion channel, 6 (P2rx6), transcript variant 2, mRNA.
Product Type ORF clone
Gene Abbr P2rx6
Species Mouse
ORF Size 1089bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Target Gene P2RX6
Background The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq, Apr 2009]
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