Mouse Orc2 ORF Clone(NM_001025378.2)

Name: Mouse Orc2 ORF Clone(NM_001025378.2)
SKU: CDCR231608
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCR231608

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Product Information

Gene Information

Cat. No.	CDCR231608
Product Type	ORF Clone
Gene Abbr	Orc2
Species	Mouse
Tag	C-terminal TurboGFP
ORF Size	1587 bp
Size	10 ug
Vector	pCMV6-AC-GFP

Target Gene

ORC2

Background

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate. [provided by RefSeq, Oct 2010]

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