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Mouse Nrg2 ORF clone (NM_001167891.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL151486

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Product Information

Gene Information

Cat. No. CDCL151486
Description Mus musculus neuregulin 2 (Nrg2), mRNA.
Product Type ORF clone
Gene Abbr Nrg2
Species Mouse
ORF Size 2574bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Target Gene NRG2
Background This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described. [provided by RefSeq, May 2010]
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