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Mouse Nfkbiz ORF Clone(NM_030612.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR263616

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Product Information

Gene Information

Cat. No. CDCR263616
Product Type ORF Clone
Gene Abbr Nfkbiz
Species Mouse
Tag C-terminal TurboGFP
ORF Size 2187 bp
Vector pCMV6-AC-GFP
Target Gene NFKBIZ
Background This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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