Mouse Nfatc4 ORF clone (NM_023699.3)

Name: Mouse Nfatc4 ORF clone (NM_023699.3)
SKU: CDCL137945
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL137945

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Product Information

Gene Information

Cat. No.	CDCL137945
Description	Mus musculus nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 (Nfatc4), transcript variant 1, mRNA.
Product Type	ORF clone
Gene Abbr	Nfatc4
Species	Mouse
ORF Size	2706bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

NFATC4

Background

This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

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