Mouse Mst1r ORF clone (NM_009074.2)

Name: Mouse Mst1r ORF clone (NM_009074.2)
SKU: CDCL151408
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL151408

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Product Information

Gene Information

Cat. No.	CDCL151408
Description	Mus musculus macrophage stimulating 1 receptor (c-met-related tyrosine kinase) (Mst1r), mRNA.
Product Type	ORF clone
Gene Abbr	Mst1r
Species	Mouse
ORF Size	4137bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

MST1R

Background

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]

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