Mouse Mapk8ip3 ORF clone (NM_001163453.1)

Name: Mouse Mapk8ip3 ORF clone (NM_001163453.1)
SKU: CDCL130539
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL130539

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Product Information

Gene Information

Cat. No.	CDCL130539
Description	Mus musculus mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 7, mRNA.
Product Type	ORF clone
Gene Abbr	Mapk8ip3
Species	Mouse
ORF Size	3903bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

MAPK8IP3

Background

The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

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