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Mouse Lrrc8a cDNA Clone(NM_177725.4)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL007149

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Gene Information

Cat. No. CDFL007149
Product Type cDNA clone
Gene Abbr Lrrc8a
Species Mouse
Size 10 ug
Vector pCMV6Entry
Target Gene LRRC8A
Background This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
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