Mouse LMX1B ORF clone (NM_001174146.1)

Name: Mouse LMX1B ORF clone (NM_001174146.1)
SKU: CDCL127769
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL127769

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Product Information

Gene Information

Cat. No.	CDCL127769
Description	Homo sapiens LIM homeobox transcription factor 1, beta (LMX1B), transcript variant 3, mRNA.
Product Type	ORF clone
Gene Abbr	LMX1B
Species	Human
ORF Size	1221bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

LMX1B

Background

This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

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