Mouse LIGHT ORF clone(NM_019418.2)

Name: Mouse LIGHT ORF clone(NM_019418.2)
SKU: CDCL185159
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL185159

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Product Information

Gene Information

Cat. No.	CDCL185159
Description	ORF Clone of Mus musculus tumor necrosis factor (ligand) superfamily, member 14 DNA.
Product Type	ORF clone
Gene Abbr	LIGHT
Species	Mouse
ORF Size	720bp
Vector	pGEM-T
Warning	This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	store at -20°C

Target Gene

TNFSF14

Background

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

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