Mouse Kcnmb3 ORF clone (NM_001195074.1)

Name: Mouse Kcnmb3 ORF clone (NM_001195074.1)
SKU: CDCL151214
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL151214

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Product Information

Gene Information

Cat. No.	CDCL151214
Description	Mus musculus potassium large conductance calcium-activated channel, subfamily M, beta member 3 (Kcnmb3), mRNA.
Product Type	ORF clone
Gene Abbr	Kcnmb3
Species	Mouse
ORF Size	720bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

KCNMB3

Background

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22. [provided by RefSeq, Jul 2009]

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