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Mouse JPH2 ORF clone (NM_020433.4)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL122453

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Product Information

Gene Information

Cat. No. CDCL122453
Description Homo sapiens junctophilin 2 (JPH2), transcript variant 1, mRNA.
Product Type ORF clone
Gene Abbr JPH2
Species Human
ORF Size 2091bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Target Gene JPH2
Background Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2008]
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