Mouse JARID2 ORF clone(NM_021878.3)

Name: Mouse JARID2 ORF clone(NM_021878.3)
SKU: CDCH387499
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCH387499

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Product Information

Gene Information

Cat. No.	CDCH387499
Product Type	ORF clone
Gene Abbr	JARID2
Species	Mouse
Host Cell	Bacterial
Source	Bacterial
ORF Size	5716bp
Size	1ug
Format	Clear Liquid
Vector	pORF
Buffer	10mM Tris-HCI, 1mM EDTA, pH8.0
Warning	pORF-mJarid2 ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage	1 year when stored at -20°C or lower in a non-frost free freezer.

Target Gene

JARID2

Background

This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]

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