Mouse Igll1 cDNA Clone(NM_001190325.1)

Name: Mouse Igll1 cDNA Clone(NM_001190325.1)
SKU: CDFG021445
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFG021445

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Product Information

Gene Information

Cat. No.	CDFG021445
Product Type	cDNA clone
Gene Abbr	Igll1
Species	Mouse
ORF Size	630bp
Size	10 ug
Vector	pCMV6Entry

Target Gene

IGLL1

Background

The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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