Mouse HOPX ORF clone (NM_001145460.1)

Name: Mouse HOPX ORF clone (NM_001145460.1)
SKU: CDCL117979
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL117979

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Product Information

Gene Information

Cat. No.	CDCL117979
Description	Homo sapiens HOP homeobox (HOPX), transcript variant 5, mRNA.
Product Type	ORF clone
Gene Abbr	HOPX
Species	Human
ORF Size	339bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

HOPX

Background

The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Feb 2009]

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