Human HDGFRP2 ORF clone (NM_001001520.1)

Name: Human HDGFRP2 ORF clone (NM_001001520.1)
SKU: CDCL116421
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL116421

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Product Information

Gene Information

Cat. No.	CDCL116421
Description	Homo sapiens hepatoma-derived growth factor-related protein 2 (HDGFRP2), transcript variant 1, mRNA.
Product Type	ORF clone
Gene Abbr	HDGFRP2
Species	Human
ORF Size	2016bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

HDGFRP2

Background

This gene encodes a member of the hepatoma-derived growth factor (HDGF) family. The protein includes an N-terminal PWWP domain that binds to methyl-lysine-containing histones, with specific binding of this protein to tri-methylated lysines 36 and 79 of histone H3, and di- and tri-methylated lysine 20 of histone H4. The protein functions in LEDGF/p75-independent HIV-1 replication by determining HIV-1 integration site selection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]

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