Mouse HCST ORF clone (NM_001007469.1)

Name: Mouse HCST ORF clone (NM_001007469.1)
SKU: CDCL116263
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL116263

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Product Information

Gene Information

Cat. No.	CDCL116263
Description	Homo sapiens hematopoietic cell signal transducer (HCST), transcript variant 2, mRNA.
Product Type	ORF clone
Gene Abbr	HCST
Species	Human
ORF Size	279bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

HCST

Background

This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex, this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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