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Mouse H2afy cDNA Clone(NM_001159513.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG019868

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Product Information

Gene Information

Cat. No. CDFG019868
Product Type cDNA clone
Gene Abbr H2afy
Species Mouse
ORF Size 1116bp
Size 10 ug
Vector pCMV6Entry
Target Gene H2AFY
Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2015]
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