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Mouse GSDMB ORF clone (NM_001165959.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCL114985

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Product Information

Gene Information

Cat. No. CDCL114985
Description Homo sapiens gasdermin B (GSDMB), transcript variant 4, mRNA.
Product Type ORF clone
Gene Abbr GSDMB
Species Human
ORF Size 1224bp
Format purified plasmid
Vector pDONR
Warning Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.
Target Gene GSDMB
Background This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Nov 2016]
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