Mouse GFM2 ORF clone(NM_177266.5)

Name: Mouse GFM2 ORF clone(NM_177266.5)
SKU: CDCG009051
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCG009051

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Product Information

Gene Information

Cat. No.	CDCG009051
Product Type	ORF clone
Gene Abbr	GFM2
Species	Mouse
Host Cell	Bacterial
Source	Bacteria
ORF Size	3203bp
Size	1ug
Format	Clear Liquid
Vector	pORF
Buffer	10mM Tris-HCI, 1mM EDTA, pH8.0
Warning	pORF-mGfm2 ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage	1 year when stored at -20°C or lower in a non-frost free freezer.

Target Gene

GFM2

Background

Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA . Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]

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