Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFG017329
| Cat. No. | CDFG017329 |
| Product Type | cDNA clone |
| Gene Abbr | Flg2 |
| Species | Mouse |
| ORF Size | 7089bp |
| Size | 10 ug |
| Vector | pCMV6Entry |
| Target Gene | FLG2 |
| Background | The filaggrin-like protein encoded by this gene is upregulated by calcium, proteolyzed by calpain 1, and is involved in epithelial homeostasis. The encoded protein is required for proper cornification in skin, with defects in this gene being associated with skin diseases. This protein also has a function in skin barrier protection. In fact, in addition to providing a physical barrier, C-terminal fragments of this protein display antimicrobial activity against P. aeruginosa and E. coli. [provided by RefSeq, Jul 2020] |
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