Mouse Fbxl5 ORF clone (NM_001159963.1)

Name: Mouse Fbxl5 ORF clone (NM_001159963.1)
SKU: CDCL107149
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL107149

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Product Information

Gene Information

Cat. No.	CDCL107149
Description	Mus musculus F-box and leucine-rich repeat protein 5 (Fbxl5), transcript variant 1, mRNA.
Product Type	ORF clone
Gene Abbr	Fbxl5
Species	Mouse
ORF Size	2073bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

FBXL5

Background

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2010]

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