Mouse FBLIM1 ORF clone (NM_001024216.1)

Name: Mouse FBLIM1 ORF clone (NM_001024216.1)
SKU: CDCL106947
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL106947

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Product Information

Gene Information

Cat. No.	CDCL106947
Description	Homo sapiens filamin binding LIM protein 1 (FBLIM1), transcript variant 3, mRNA.
Product Type	ORF clone
Gene Abbr	FBLIM1
Species	Human
ORF Size	831bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

FBLIM1

Background

This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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